- Estudios clínicos
- Comparison of 2chlorhexidine mouthwashes on plaque regrowth in vivo and dietary staining in vitro
Comparison of 2chlorhexidine mouthwashes on plaque regrowth in vivo and dietary staining in vitro
Until recently, the few available chlorhexidine mouthrinse products have been 0.2% formulations. However, concentrations of 0.12'/Q chlorhexidine appear as effective as 0.2°/j. if the volume of the rinse is increased to 15 ml. Since the mere incorporation of chlorhexidine in a formulation does not guarentee availability of the antiseptic, it would seem reasonable to evaluate or compare all products. This is particularly the case when other ingredients, such as fluoride are added. The 1st study compared the effect of a 0.12% chlorhexidine rinse with a 0.12% chlorhexidine/0.022'Ki sodium fluoride rinse for effects on plaque re- growth. The study was a 7-day, blind, randomised, 2-cen cross-over design with a baseline control run in period, in which 18 subjects participated. Both chlorhex- idine products significantly reduced plaque compared to control but the chlorhex- idine fluoride rinse was less effective than the chlorhexidine only rinse. The 2nd study assessed the propensity of the chlorhexidine rinses to induce dietary staining in vitro. For the chlorhexidine fluoride rinse, this was less than the other 0.12% rinse and a commonly used 0.2% product. The data in vivo and in vitro suggest reduced chlorhexidine availability from appears to cause some loss of efficacy.
Apúntate al sistema de alertas y estarás al día de las últimas actualizaciones
- Periodontal pathogens and tetracycline resistance genes in subgingival biofilm of periodontally healthy and diseased Dominican adults
- The efficacy of a topical sialogogue spray containing 1% malic acid in patients with antidepressant-induced dry mouth: a double-blind, randomized clinical trial.
- Eficacia del spray de ácido málico 1% (Xeros Dentaid spray©) en el tratamiento de la xerostomía inducida por fármacos