Estudios clínicos

A randomized clinical trial on the short-term clinical and microbiological effects of the adjunctive use of a 0.05% chlorhexidine mouth rinse for patients in supportive periodontal care

DESCRIPCIÓN

Objective: 

To evaluate the clinical and microbiological activity of a new mouth rinse formulation, used as an adjunct to oral hygiene, for patients in supportive periodontal care. 

Patients and Methods:

 This was a randomized, placebo-controlled clinical trial with two groups: test group, rinsing twice per day with the test product (with 0.05% chlorhexidine and 0.05% cetylpyridinium chloride); and control group, rinsing with a placebo. Treated chronic periodontitis patients were included, and two visits were rendered, baseline, and after 15 days. Clinical outcome variables included plaque and gingival indices, and probing pocket depth. Subgingival samples were processed by culturing. Patient-based variables and adverse effects were also assessed. Outcome variables were compared by t-test, w2, and Mann–Whitney test.

Results:

The results belonged to 33 patients. Plaque and gingival indices, and the log of bacterial total counts were reduced in the test group (p40.01), but differences between groups were only statistically significant (po0.05) for plaque and bacterial counts. A significant reduction in the proportions of flora ( po0.05) and frequency of detection ( p 5 0.01) of Porphyromonas gingivalis was observed in the test group. 

Conclusions: 

The newly formulated mouth rinse demonstrated short-term plaque- inhibitory activity. This was associated with a reduction in the total load of anaerobic subgingival microflora.

ETIQUETAS

Volver al listado de estudios
¡NO TE PIERDAS
NINGÚN CURSO!

Apúntate al sistema de alertas y estarás al día de las últimas actualizaciones

ESTUDIOS RELACIONADOS

  • Periodontal pathogens and tetracycline resistance genes in subgingival biofilm of periodontally healthy and diseased Dominican adults
    Más info
  • The efficacy of a topical sialogogue spray containing 1% malic acid in patients with antidepressant-induced dry mouth: a double-blind, randomized clinical trial.
    Más info
  • Eficacia del spray de ácido málico 1% (Xeros Dentaid spray©) en el tratamiento de la xerostomía inducida por fármacos
    Más info

¿TE PODEMOS AYUDAR?  
Envía tu consulta y pronto uno de nuestros especialistas se pondrá en contacto contigo.
  • Antes de cumplimentar el presente formulario , en su caso, prestar el consentimiento al tratamiento de sus datos, debe leer la información básica sobre protección de datos que se presenta Aquí